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Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget’s disease of bone

Paget’s disease is characterized by highly localized areas of increased osteoclast (OCL) activity. This suggests that the microenvironment in pagetic lesions is highly osteoclastogenic, or that OCL precursors in these lesions are hyperresponsive to osteoclastogenic factors (or both). To examine thes...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Menaa, Cheikh, Reddy, Sakamuri V., Kurihara, Noriyoshi, Maeda, Hidefumi, Anderson, Dirk, Cundy, Tim, Cornish, Jillian, Singer, Frederick R., Bruder, Jan M., Roodman, G. David
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC378510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10862799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9133
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