Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget’s disease of bone

Paget’s disease is characterized by highly localized areas of increased osteoclast (OCL) activity. This suggests that the microenvironment in pagetic lesions is highly osteoclastogenic, or that OCL precursors in these lesions are hyperresponsive to osteoclastogenic factors (or both). To examine thes...

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Pubblicato in:	J Clin Invest
Autori principali:	Menaa, Cheikh, Reddy, Sakamuri V., Kurihara, Noriyoshi, Maeda, Hidefumi, Anderson, Dirk, Cundy, Tim, Cornish, Jillian, Singer, Frederick R., Bruder, Jan M., Roodman, G. David
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC378510/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10862799/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9133
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