Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation
We previously reported that measles virus nucleocapsid protein (MVNP) expression in osteoclasts (OCLs) of patients with Paget disease (PD) or targeted to the OCL lineage in MVNP-transgenic mice (MVNP mice) increases IGF1 production in osteoclasts (OCL-IGF1) and leads to development of PD OCLs and pa...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
American Society for Clinical investigation
2023-07-01
|
| Rangatū: | JCI Insight |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1172/jci.insight.159838 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|