Pro-Inflammatory Cytokine Induction of 11β-hydroxysteroid Dehydrogenase Type 1 in A549 Cells Requires Phosphorylation of C/EBPβ at Thr235

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts inert glucocorticoids into active forms, thereby increasing intracellular glucocorticoid levels, important to restrain acute inflammation. 11β-HSD1 is induced by pro-inflammatory cytokines in a variety of cells. Here, we show 11β-HSD1 expre...

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Detalhes bibliográficos
Main Authors: Esteves, Cristina L., Verma, Manu, Róg-Zielińska, Ewa, Kelly, Val, Sai, Shuji, Breton, Amandine, Donadeu, Francesc X., Seckl, Jonathan R., Chapman, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784397/
https://ncbi.nlm.nih.gov/pubmed/24086653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075874
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