Regulation of Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) by CCAAT/Enhancer-Binding Protein (C/EBP) β Isoforms, LIP and LAP

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyses intracellular regeneration of active glucocorticoids, notably in liver and adipose tissue. 11β-HSD1 is increased selectively in adipose tissue in human obesity, a change implicated in the pathogenesis of metabolic syndrome. With high fat (...

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Autors principals: Esteves, Cristina L., Kelly, Val, Bégay, Valérie, Man, Tak Y., Morton, Nicholas M., Leutz, Achim, Seckl, Jonathan R., Chapman, Karen E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360670/
https://ncbi.nlm.nih.gov/pubmed/22662254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037953
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