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Does epithelial sodium channel hyperactivity contribute to cystic fibrosis lung disease?
Airway epithelia absorb Na(+) through the epithelial Na(+) channel (ENaC) and secrete Cl(−) through the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. This balance maintains sufficient airway surface liquid hydration to permit efficient mucus clearance, which is needed to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784186/ https://ncbi.nlm.nih.gov/pubmed/23878362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.240861 |
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