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Reduction of Human Defensin 5 Affords a High-Affinity Zinc-Chelating Peptide
Human defensin 5 (HD5) is a 32-residue cysteine-rich host-defense peptide that exhibits three disulfide bonds in the oxidized form (HD5(ox)). It is abundant in small intestinal Paneth cells, which release HD5 into the intestinal lumen and house a labile Zn(II) store of unknown function. Here we cons...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783636/ https://ncbi.nlm.nih.gov/pubmed/23841778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400340k |
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