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Reduction of Human Defensin 5 Affords a High-Affinity Zinc-Chelating Peptide

Human defensin 5 (HD5) is a 32-residue cysteine-rich host-defense peptide that exhibits three disulfide bonds in the oxidized form (HD5(ox)). It is abundant in small intestinal Paneth cells, which release HD5 into the intestinal lumen and house a labile Zn(II) store of unknown function. Here we cons...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Yunfei, Cougnon, Fabien B. L., Wanniarachchi, Yoshitha A., Hayden, Joshua A., Nolan, Elizabeth M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783636/
https://ncbi.nlm.nih.gov/pubmed/23841778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400340k
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