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NMR Solution Structure and Condition-Dependent Oligomerization of the Antimicrobial Peptide Human Defensin 5

Human defensin 5 (HD5) is a 32-residue host-defense peptide expressed in the gastrointestinal, reproductive, and urinary tracts that has antimicrobial activity. It exhibits six cysteine residues that are regiospecifically oxidized to form three disulfide bonds (Cys(3)—Cys(31), Cys(5)—Cys(20), and Cy...

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Detalhes bibliográficos
Main Authors: Wommack, Andrew J., Robson, Scott A., Wanniarachchi, Yoshitha A., Wan, Andrea, Turner, Christopher J., Wagner, Gerhard, Nolan, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579768/
https://ncbi.nlm.nih.gov/pubmed/23163963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301255u
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