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Avidity Modulation of Folate-Targeted Multivalent Dendrimers for Evaluating Biophysical Models of Cancer Targeting Nanoparticles
We investigated two types of generation 5 polyamidoamine (PAMAM) dendrimers, each conjugated stochastically with a mean number of five or ten methotrexate (MTX) ligands per dendrimer (G5-MTX(5), G5-MTX(10)), for their binding to surface-immobilized folate binding protein (FBP) as a function of recep...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783574/ https://ncbi.nlm.nih.gov/pubmed/23855478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400258d |
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