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Polyvalent Dendrimer-Methotrexate as a Folate Receptor-Targeted Cancer Therapeutic
Our previous studies have demonstrated that a generation 5 dendrimer (G5) conjugated with both folic acid (FA) and methotrexate (MTX) has a higher chemotherapeutic index than MTX alone. Despite this, batch-to-batch inconsistencies in the number of FA and MTX molecules linked to each dendrimer led to...
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| Publicado no: | Mol Pharm |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457335/ https://ncbi.nlm.nih.gov/pubmed/22827500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3002232 |
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