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Polyvalent Saccharide-Functionalized Generation 3 Poly (amidoamine) Dendrimer-Methotrexate Conjugate as a Potential Anticancer Agent
A saccharide-terminated Generation 3 (G3) polyamidoamine (PAMAM) dendrimer was synthesized as a drug carrier. Utilizing this dendritic platform, we have successfully synthesized polyvalent conjugates (G3-MTX) containing the drug methotrexate (MTX). Surface plasmon resonance (SPR) results showed that...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130541/ https://ncbi.nlm.nih.gov/pubmed/21459000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.03.019 |
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