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Photochemical Release of Methotrexate from Folate Receptor-Targeting PAMAM Dendrimer Nanoconjugate
Nanoparticle (NP)-based targeted drug delivery involves cell-specific targeting followed by a subsequent therapeutic action from the therapeutic carried by the NP system. NPs conjugated with methotrexate (MTX), a potent inhibitor of dihydrofolate reductase (DHFR) localized in cytosol, have been unde...
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| Publicado en: | Photochem Photobiol Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457390/ https://ncbi.nlm.nih.gov/pubmed/22234658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2pp05355a |
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