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Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery

This communication describes the synthesis and in vitro biological evaluation of novel generation 5 PAMAM dendrimers conjugated with riboflavin as a targeting ligand. Cell-based experiments demonstrated that a dendrimer conjugated with riboflavin is able to undergo cellular binding and uptake in KB...

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Detalhes bibliográficos
Main Authors: Thomas, Thommey P., Choi, Seok Ki, Li, Ming-Hsin, Kotlyar, Alina, Baker, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922453/
https://ncbi.nlm.nih.gov/pubmed/20659800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.07.005
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