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Could yeast prion domains originate from polyQ/N tracts?

A significant body of evidence shows that polyglutamine (polyQ) tracts are important for various biological functions. The characteristic polymorphism of polyQ length is thought to play an important role in the adaptation of organisms to their environment. However, proteins with expanded polyQ are p...

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Detalhes bibliográficos
Main Authors: Alexandrov, Alexander I., Ter-Avanesyan, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783105/
https://ncbi.nlm.nih.gov/pubmed/23764835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.24628
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