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Systemic Delivery of shRNA by AAV9 Provides Highly Efficient Knockdown of Ubiquitously Expressed GFP in Mouse Heart, but Not Liver

AAV9 is a powerful gene delivery vehicle capable of providing long-term gene expression in a variety of cell types, particularly cardiomyocytes. The use of AAV-delivery for RNA interference is an intense area of research, but a comprehensive analysis of knockdown in cardiac and liver tissues after s...

詳細記述

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書誌詳細
主要な著者: Piras, Bryan A., O’Connor, Daniel M., French, Brent A.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782464/
https://ncbi.nlm.nih.gov/pubmed/24086659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075894
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