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AAV Delivery of Endothelin-1 shRNA Attenuates Cold-Induced Hypertension

Cold temperatures are associated with increased prevalence of hypertension. Cold exposure increases endothelin-1 (ET1) production. The purpose of this study is to determine whether upregulation of ET1 contributes to cold-induced hypertension (CIH). In vivo RNAi silencing of the ET1 gene was achieved...

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Bibliografiska uppgifter
I publikationen:Hum Gene Ther
Huvudupphovsmän: Chen, Peter Gin-Fu, Sun, Zhongjie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312589/
https://ncbi.nlm.nih.gov/pubmed/27736201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.047
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