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Delivery of Therapeutic AGT shRNA by PEG-Bu for Hypertension Therapy

Gene silencing by RNA interference (RNAi) is a promising approach for gene therapy. However, up to today, it is still a major challenge to find safe and efficient non-viral vectors. Previously, we reported PEI-Bu, a small molecular weight PEI derivative, as an efficient non-viral carrier. However, l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yu-Qiang, Wang, Fei, Deng, Xiao-Qin, Sheng, Jing, Chen, Shu-Yan, Su, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716693/
https://ncbi.nlm.nih.gov/pubmed/23894329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068651
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