AAV Delivery of shRNA Against TRPC6 in Mouse Hippocampus Impairs Cognitive Function

Transient Receptor Potential Canonical 6 (TRPC6) has been suggested to be involved in synapse function and contribute to hippocampal-dependent cognitive processes. Gene silencing of TRPC6 was performed by injecting adeno-associated virus (AAV) expressing TRPC6-specific shRNA (shRNA-TRPC6) into the h...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Xie, Ruxin, Wang, Zhongke, Liu, Tianyao, Xiao, Rui, Lv, Keyi, Wu, Chuan, Luo, Yi, Cai, Yun, Fan, Xiaotang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313999/
https://ncbi.nlm.nih.gov/pubmed/34327201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.688655
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