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Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization
Molecular dynamics simulations are used to model proteins that diffuse to DNA, bind, and dissociate; in the absence of any explicit interaction between proteins, or between templates, binding spontaneously induces local DNA compaction and protein aggregation. Small bivalent proteins form into rows [...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780866/ https://ncbi.nlm.nih.gov/pubmed/24003126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302950110 |
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