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Nucleosome positions alone can be used to predict domains in yeast chromosomes

We use molecular dynamics simulations based on publicly available micrococcal nuclease sequencing data for nucleosome positions to predict the 3D structure of chromatin in the yeast genome. Our main aim is to shed light on the mechanism underlying the formation of chromosomal interaction domains, ch...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wiese, Oliver, Marenduzzo, Davide, Brackley, Chris A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717315/
https://ncbi.nlm.nih.gov/pubmed/31416914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817829116
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