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Sequence-based prediction of single nucleosome positioning and genome-wide nucleosome occupancy

Nucleosome positioning dictates eukaryotic DNA compaction and access. To predict nucleosome positions in a statistical mechanics model, we exploited the knowledge that nucleosomes favor DNA sequences with specific periodically occurring dinucleotides. Our model is the first to capture both dyad posi...

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Detalhes bibliográficos
Main Authors: van der Heijden, Thijn, van Vugt, Joke J.F.A., Logie, Colin, van Noort, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458375/
https://ncbi.nlm.nih.gov/pubmed/22908247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205659109
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