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Sequence-based prediction of single nucleosome positioning and genome-wide nucleosome occupancy
Nucleosome positioning dictates eukaryotic DNA compaction and access. To predict nucleosome positions in a statistical mechanics model, we exploited the knowledge that nucleosomes favor DNA sequences with specific periodically occurring dinucleotides. Our model is the first to capture both dyad posi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458375/ https://ncbi.nlm.nih.gov/pubmed/22908247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205659109 |
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