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Polymorphisms of p21 and p27 Jointly Contribute to an Earlier Age at Diagnosis of Pancreatic Cancer

p21 and p27, members of the kinase inhibitor protein (KIP) family, bind to cyclin-CDK complexes to inhibit their catalytic activity and induce cell cycle arrest. The purpose of our study was to identify whether the p21 (C-to-A), and p27 (T-to-G) polymorphisms were associated with age at diagnosis of...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Jinyun, Killary, Ann M., Sen, Subrata, Amos, Christopher I., Evans, Douglas B., Abbruzzese, James L., Frazier, Marsha L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780599/
https://ncbi.nlm.nih.gov/pubmed/18694622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.06.022
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