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Aurora-A and p16 Polymorphisms Contribute to an EarlierAge at Diagnosis of Pancreatic Cancer in Caucasians

PURPOSE: Aurora-A and p16 play a major role in cell cycle checkpoint regulation. Both of them are important in the maintenance of centrosome duplication. Therefore, we hypothesized that polymorphisms in the two genes may interact or work together to influence the finely tuned mechanisms of cell cycl...

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Detalhes bibliográficos
Main Authors: Chen, Jinyun, Li, Donghui, Wei, Chongjuan, Sen, Subrata, Killary, Ann M., Amos, Christopher I., Evans, Douglas B., Abbruzzese, James L., Frazier, Marsha L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365501/
https://ncbi.nlm.nih.gov/pubmed/17505013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-2319
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