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Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic whites: a case-control study

OBJECTIVES: p21 (WAF1/Cip1/CDKN1A) and p27 (Kip1/CDKN1B) are members of the Cip/Kip family of cyclin-dependent kinase inhibitors, which can induce cell cycle arrest and serve as tumor suppressors. We hypothesized that genetic variants in p21 and p27 may modify individual susceptibility to pancreatic...

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Detalhes bibliográficos
Main Authors: Chen, Jinyun, Amos, Christopher I., Merriman, Kelly W., Wei, Qingyi, Sen, Subrata, Killary, Ann M., Frazier, Marsha L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796289/
https://ncbi.nlm.nih.gov/pubmed/19910837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181bd51c8
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