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Putative Tumor Suppressor Gene SEL1L Was Downregulated by Aberrantly Upregulated hsa-mir-155 in Human Pancreatic Ductal Adenocarcinoma

Sel-1-like (SEL1L) is a putative tumor suppressor gene that is significantly downregulated in human pancreatic ductal adenocarcinoma (PDA). The mechanism of the downregulation is unclear. Here, we investigated whether aberrantly upregulated microRNAs (miRNAs) repressed the expression of SEL1L. From...

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Bibliographic Details
Main Authors: Liu, Qian, Chen, Jinyun, Wang, Jin, Amos, Christopher, Killary, Ann M., Sen, Subrata, Wei, Chongjuan, Frazier, Marsha L.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887131/
https://ncbi.nlm.nih.gov/pubmed/23661430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22023
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