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Polymorphisms of p21 and p27 Jointly Contribute to an Earlier Age at Diagnosis of Pancreatic Cancer
p21 and p27, members of the kinase inhibitor protein (KIP) family, bind to cyclin-CDK complexes to inhibit their catalytic activity and induce cell cycle arrest. The purpose of our study was to identify whether the p21 (C-to-A), and p27 (T-to-G) polymorphisms were associated with age at diagnosis of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780599/ https://ncbi.nlm.nih.gov/pubmed/18694622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.06.022 |
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