Stabilities of Uracil and Pyridone-Based Carbanions: A Systematic Study in the Gas Phase and Solution and Implications for the Mechanism of Orotidine-5′-Monophosphate Decarboxylase

Lignende værker

• Polarization in the Structures of Uracil and Thiouracils: Implication for Binding with Orotidine 5’-Monophosphate Decarboxylase
  af: Huang, Sha, et al.
  Udgivet: (2011)
• The Stability of 6-Carbanion of Uracil Analogues: Mechanistic Implications for Model Reactions of Orotidine-5’-Monophosphate Decarboxylas
  af: Wong, Freeman M., et al.
  Udgivet: (2006)
• Proton Transfer from C-6 of Uridine 5′-Monophosphate Catalyzed by Orotidine 5′-Monophosphate Decarboxylase: Formation and Stability of a Vinyl Carbanion Intermediate and the Effect of a 5-Fluoro Substituent
  af: Tsang, Wing-Yin, et al.
  Udgivet: (2012)
• Product Deuterium Isotope Effect for Orotidine 5'-Monophosphate Decarboxylase: Evidence for the Existence of a Short-Lived Carbanion Intermediate
  af: Toth, Krisztina, et al.
  Udgivet: (2007)
• Formation and Stability of a Vinyl Carbanion at the Active Site of Orotidine 5′-Monophosphate Decarboxylase: pK(a) of the C-6 Proton of Enzyme-Bound UMP
  af: Amyes, Tina L., et al.
  Udgivet: (2008)