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Polarization in the Structures of Uracil and Thiouracils: Implication for Binding with Orotidine 5’-Monophosphate Decarboxylase

The structures of the uracil and thiouracils were examined using NMR spectroscopy and crystal structure data when available. The relationships between the extent of polarization and the C5–C6 bond length as well as the H5–H6 coupling constants were probed. It was found that the bond length and coupl...

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Detalhes bibliográficos
Main Authors: Huang, Sha, Gronert, Scott, Wu, Weiming
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190085/
https://ncbi.nlm.nih.gov/pubmed/21937230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.08.109
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