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Ruthenium Catalyzed Reductive Coupling of Paraformaldehyde to Trifluoromethyl Allenes: CF(3)-Bearing All-Carbon Quaternary Centers

[Image: see text] Trifluoromethyl substituted allenes engage in ruthenium catalyzed reductive couplings with paraformaldehyde to form products of hydrohydroxymethylation as single regioisomers. This method enables generation of CF(3)-bearing all-carbon quaternary stereocenters.

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sam, Brannon, Montgomery, T. Patrick, Krische, Michael J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779475/
https://ncbi.nlm.nih.gov/pubmed/23841678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401771a
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