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Alzheimer’s Amyloid-β Oligomers Rescue Cellular Prion Protein Induced Tau Reduction via the Fyn Pathway
[Image: see text] Amyloid-β (Aβ) and tau are the pathogenic hallmarks in Alzheimer’s disease (AD). Aβ oligomers are considered the actual toxic entities, and the toxicity relies on the presence of tau. Recently, Aβ oligomers have been shown to specifically interact with cellular prion protein (PrP(C...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778425/ https://ncbi.nlm.nih.gov/pubmed/23805846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400085q |
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