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Alzheimer’s Amyloid-β Oligomers Rescue Cellular Prion Protein Induced Tau Reduction via the Fyn Pathway

[Image: see text] Amyloid-β (Aβ) and tau are the pathogenic hallmarks in Alzheimer’s disease (AD). Aβ oligomers are considered the actual toxic entities, and the toxicity relies on the presence of tau. Recently, Aβ oligomers have been shown to specifically interact with cellular prion protein (PrP(C...

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מידע ביבליוגרפי
Main Authors: Chen, Rong-Jie, Chang, Wei-Wei, Lin, Yu-Chun, Cheng, Pei-Lin, Chen, Yun-Ru
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2013
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778425/
https://ncbi.nlm.nih.gov/pubmed/23805846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400085q
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