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The assembly, activation, and substrate specificity of Cyclin D1/Cdk2 complexes

Previous studies have shown conflicting data regarding Cyclin D1/Cdk2 complexes and, considering the widespread overexpression of Cyclin D1 in cancer, it is important to fully understand their relevance. While many have shown Cyclin D1/Cdk2 complexes to form active complexes, others have failed to s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jahn, Stephan C., Law, Mary E., Corsino, Patrick E., Rowe, Thomas C., Davis, Bradley J., Law, Brian K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778134/
https://ncbi.nlm.nih.gov/pubmed/23627734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400047u
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