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Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes

In eukaryotes, cell cycle progression is controlled by cyclin/cyclin-dependent kinase (CDK) pairs. To better understand the details of this process, it is necessary to dissect the CDK’s substrate pool in a cyclin- and cell cycle stage-specific way. Here, we report a mass spectrometry-based method th...

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Sonraí Bibleagrafaíochta
Main Authors: Li, Yinyin, Cross, Frederick R., Chait, Brian T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128132/
https://ncbi.nlm.nih.gov/pubmed/25049391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409666111
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