Ultra-sensitive fluorescent proteins for imaging neuronal activity

Fluorescent calcium sensors are widely used to image neural activity. Using structure-based mutagenesis and neuron-based screening, we developed a family of ultra-sensitive protein calcium sensors (GCaMP6) that outperformed other sensors in cultured neurons and in zebrafish, flies, and mice in vivo....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Chen, Tsai-Wen, Wardill, Trevor J., Sun, Yi, Pulver, Stefan R., Renninger, Sabine L., Baohan, Amy, Schreiter, Eric R., Kerr, Rex A., Orger, Michael B., Jayaraman, Vivek, Looger, Loren L., Svoboda, Karel, Kim, Douglas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777791/
https://ncbi.nlm.nih.gov/pubmed/23868258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12354
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky