A Neuron-Based Screening Platform for Optimizing Genetically-Encoded Calcium Indicators

Fluorescent protein-based sensors for detecting neuronal activity have been developed largely based on non-neuronal screening systems. However, the dynamics of neuronal state variables (e.g., voltage, calcium, etc.) are typically very rapid compared to those of non-excitable cells. We developed an e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wardill, Trevor J., Chen, Tsai-Wen, Schreiter, Eric R., Hasseman, Jeremy P., Tsegaye, Getahun, Fosque, Benjamin F., Behnam, Reza, Shields, Brenda C., Ramirez, Melissa, Kimmel, Bruce E., Kerr, Rex A., Jayaraman, Vivek, Looger, Loren L., Svoboda, Karel, Kim, Douglas S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796516/
https://ncbi.nlm.nih.gov/pubmed/24155972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077728
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