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Targeting tumors with nonreplicating Toxoplasma gondii uracil auxotroph vaccines
Toxoplasma gondii is an intracellular parasite that has evolved to actively control its invaded host cells. Toxoplasma triggers then actively regulates host innate IL-12 and interferon-γ responses that elicit T cell control of infection. A live, nonreplicating avirulent uracil auxotroph vaccine stra...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777737/ https://ncbi.nlm.nih.gov/pubmed/23928100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2013.07.001 |
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