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Non-replicating Toxoplasma gondii reverses tumor-associated immunosuppression

We examined the efficacy of using attenuated non-replicating Toxoplasma gondii uracil auxotrophs that can be safely delivered as anticancer immunotherapeutics. This strategy exerted remarkable therapeutic activity in murine models of melanoma and ovarian carcinoma, and holds broad potential for the...

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Detalhes bibliográficos
Main Authors: Fox, Barbara A, Sanders, Kiah L, Bzik, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862683/
https://ncbi.nlm.nih.gov/pubmed/24353916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26296
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