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Targeting tumors with nonreplicating Toxoplasma gondii uracil auxotroph vaccines

Toxoplasma gondii is an intracellular parasite that has evolved to actively control its invaded host cells. Toxoplasma triggers then actively regulates host innate IL-12 and interferon-γ responses that elicit T cell control of infection. A live, nonreplicating avirulent uracil auxotroph vaccine stra...

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Bibliografische gegevens
Hoofdauteurs: Fox, Barbara A., Sanders, Kiah L., Chen, Shan, Bzik, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777737/
https://ncbi.nlm.nih.gov/pubmed/23928100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2013.07.001
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