Poliovirus 2A Protease Triggers a Selective Nucleo-Cytoplasmic Redistribution of Splicing Factors to Regulate Alternative Pre-mRNA Splicing

Poliovirus protease 2A (2A(pro)) obstructs host gene expression by reprogramming transcriptional and post-transcriptional regulatory events during infection. Here we demonstrate that expression of 2A(pro) induces a selective nucleo-cytoplasm translocation of several important RNA binding proteins an...

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Autores principales: Álvarez, Enrique, Castelló, Alfredo, Carrasco, Luis, Izquierdo, José M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774746/
https://ncbi.nlm.nih.gov/pubmed/24066065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073723
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