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Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA
Pre-mRNA splicing deposits multi-protein complexes, termed exon junction complexes (EJCs), on mRNAs near exon-exon junctions. The core of EJC consists of four proteins, eIF4AIII, MLN51, Y14 and Magoh. Y14 is a nuclear protein that can shuttle between the nucleus and the cytoplasm, and binds specific...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216578/ https://ncbi.nlm.nih.gov/pubmed/22355610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00092 |
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