The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Both microRNAs and alternative pre-mRNA splicing have been implicated in the development of the nervous system (NS), but functional interactions between these two pathways are poorly understood. We demonstrate that the neuron-specific microRNA miR-124 directly targets PTBP1 (PTB/hnRNP I) mRNA, which...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Makeyev, Eugene V., Zhang, Jiangwen, Carrasco, Monica A., Maniatis, Tom
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139456/
https://ncbi.nlm.nih.gov/pubmed/17679093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.07.015
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki