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Non-coding functions of alternative pre-mRNA splicing in development

A majority of messenger RNA precursors (pre-mRNAs) in the higher eukaryotes undergo alternative splicing to generate more than one mature product. By targeting the open reading frame region this process increases diversity of protein isoforms beyond the nominal coding capacity of the genome. However...

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Publicat a:Semin Cell Dev Biol
Autors principals: Mockenhaupt, Stefan, Makeyev, Eugene V.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683092/
https://ncbi.nlm.nih.gov/pubmed/26493705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2015.10.018
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