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Non-coding functions of alternative pre-mRNA splicing in development

A majority of messenger RNA precursors (pre-mRNAs) in the higher eukaryotes undergo alternative splicing to generate more than one mature product. By targeting the open reading frame region this process increases diversity of protein isoforms beyond the nominal coding capacity of the genome. However...

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Bibliographic Details
Published in:Semin Cell Dev Biol
Main Authors: Mockenhaupt, Stefan, Makeyev, Eugene V.
Format: Artigo
Language:Inglês
Published: Academic Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683092/
https://ncbi.nlm.nih.gov/pubmed/26493705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2015.10.018
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