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The Multifaceted Poliovirus 2A Protease: Regulation of Gene Expression by Picornavirus Proteases

After entry into animal cells, most viruses hijack essential components involved in gene expression. This is the case of poliovirus, which abrogates cellular translation soon after virus internalization. Abrogation is achieved by cleavage of both eIF4GI and eIF4GII by the viral protease 2A. Apart fr...

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Bibliografiske detaljer
Main Authors: Castelló, Alfredo, Álvarez, Enrique, Carrasco, Luis
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085340/
https://ncbi.nlm.nih.gov/pubmed/21541224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/369648
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