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The Multifaceted Poliovirus 2A Protease: Regulation of Gene Expression by Picornavirus Proteases

After entry into animal cells, most viruses hijack essential components involved in gene expression. This is the case of poliovirus, which abrogates cellular translation soon after virus internalization. Abrogation is achieved by cleavage of both eIF4GI and eIF4GII by the viral protease 2A. Apart fr...

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Detalhes bibliográficos
Main Authors: Castelló, Alfredo, Álvarez, Enrique, Carrasco, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085340/
https://ncbi.nlm.nih.gov/pubmed/21541224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/369648
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