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A Stable HeLa Cell Line That Inducibly Expresses Poliovirus 2A(pro): Effects on Cellular and Viral Gene Expression

A HeLa cell clone (2A7d) that inducibly expresses the gene for poliovirus protease 2A (2A(pro)) under the control of tetracycline has been obtained. Synthesis of 2A(pro) induces severe morphological changes in 2A7d cells. One day after tetracycline removal, cells round up and a few hours later die....

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書誌詳細
主要な著者: Barco, Angel, Feduchi, Elena, Carrasco, Luis
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC111720/
https://ncbi.nlm.nih.gov/pubmed/10666269
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