Impaired Binding of Standard Initiation Factors Mediates Poliovirus Translation Attenuation

In the oral poliovirus vaccine, three attenuated virus strains generated by Albert Sabin are used. However, insufficient genetic stability of these strains causes major problems in poliovirus eradication. In infected cells, translation of the plus-strand poliovirus RNA genome is directed by the inte...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ochs, Kerstin, Zeller, Amandus, Saleh, Lanja, Bassili, Gergis, Song, Yutong, Sonntag, Anja, Niepmann, Michael
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.115-122.2003
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