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Impaired Binding of Standard Initiation Factors Mediates Poliovirus Translation Attenuation
In the oral poliovirus vaccine, three attenuated virus strains generated by Albert Sabin are used. However, insufficient genetic stability of these strains causes major problems in poliovirus eradication. In infected cells, translation of the plus-strand poliovirus RNA genome is directed by the inte...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140626/ https://ncbi.nlm.nih.gov/pubmed/12477816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.115-122.2003 |
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