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Impaired Binding of Standard Initiation Factors Mediates Poliovirus Translation Attenuation

In the oral poliovirus vaccine, three attenuated virus strains generated by Albert Sabin are used. However, insufficient genetic stability of these strains causes major problems in poliovirus eradication. In infected cells, translation of the plus-strand poliovirus RNA genome is directed by the inte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Ochs, Kerstin, Zeller, Amandus, Saleh, Lanja, Bassili, Gergis, Song, Yutong, Sonntag, Anja, Niepmann, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.115-122.2003
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