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Impaired Binding of Standard Initiation Factors Mediates Poliovirus Translation Attenuation

In the oral poliovirus vaccine, three attenuated virus strains generated by Albert Sabin are used. However, insufficient genetic stability of these strains causes major problems in poliovirus eradication. In infected cells, translation of the plus-strand poliovirus RNA genome is directed by the inte...

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Bibliografske podrobnosti
Main Authors: Ochs, Kerstin, Zeller, Amandus, Saleh, Lanja, Bassili, Gergis, Song, Yutong, Sonntag, Anja, Niepmann, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC140626/
https://ncbi.nlm.nih.gov/pubmed/12477816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.115-122.2003
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