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Impaired Binding of Standard Initiation Factors Mediates Poliovirus Translation Attenuation

In the oral poliovirus vaccine, three attenuated virus strains generated by Albert Sabin are used. However, insufficient genetic stability of these strains causes major problems in poliovirus eradication. In infected cells, translation of the plus-strand poliovirus RNA genome is directed by the inte...

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Библиографические подробности
Главные авторы: Ochs, Kerstin, Zeller, Amandus, Saleh, Lanja, Bassili, Gergis, Song, Yutong, Sonntag, Anja, Niepmann, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC140626/
https://ncbi.nlm.nih.gov/pubmed/12477816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.115-122.2003
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