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Translation without eIF2 Promoted by Poliovirus 2A Protease

Poliovirus RNA utilizes eIF2 for the initiation of translation in cell free systems. Remarkably, we now describe that poliovirus translation takes place at late times of infection when eIF2 is inactivated by phosphorylation. By contrast, translation directed by poliovirus RNA is blocked when eIF2 is...

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Detalhes bibliográficos
Main Authors: Redondo, Natalia, Sanz, Miguel Angel, Welnowska, Ewelina, Carrasco, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189197/
https://ncbi.nlm.nih.gov/pubmed/22003403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025699
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